Article
Correlation between a gene polymorphism of tumor necrosis factor and inflammatory bowel disease.
Chinese journal of digestive diseases - 1 Jan 2005
Song Ying, Wu Kai Chun, Zhang Li, Hao Zhi Ming, Li Hong Tao, Zhang Ling Xia, Qiao Tai Dong, Li Cai Ning, Fan Dai Ming
Abstract excerpt
OBJECTIVES: To analyze polymorphism of the tumor necrosis factor (TNF) gene in inflammatory bowel disease (IBD) patients from the Han Chinese ethnic group, and to investigate the role of polymorphism in the pathogenesis of IBD. METHODS: Polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP) techniques were used to analyze gene polymorphisms in the TNF-alpha and TNF-beta genes in 131...
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