Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Relationship between the polymorphism of tumor necrosis factor-α-308 G>A and susceptibility to inflammatory bowel diseases and colorectal cancer: a meta-analysis.

European journal of human genetics : EJHG - 1 Apr 2011

Fan Wang, Maoqing Wang, Wangyang Chen, Fulan Hu, Dandan Li, Jiaojiao Ren, Xinshu Dong, Binbin Cui, Yashuang Zhao

Abstract excerpt

Inflammatory bowel disease (IBD) and colorectal cancer (CRC) are common health problems worldwide. Tumor necrosis factor (TNF) is a type of cytokine that induces inflammation and inhibits tumorigenesis. Several studies have assessed the relationship between the polymorphism of TNF-α-308 G>A and the susceptibility to IBD and CRC; however, the results have been controversial. In addition, the hypothesis whether the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to Colitis, Ulcerative

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colorectal Neoplasms

Share to Crohn Disease

Share to Cytokines

Share to Inflammatory Bowel Diseases

Share to Tumor Necrosis Factor-alpha

Share to White People

Source

Open in PubMed Open full text

Identifiers

PMID: 21248737
DOI: 10.1038/ejhg.2010.159
PMCID: PMC3060311

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Relationship between the polymorphism of tumor necrosis factor-α-308 G>A and susceptibility to inflammatory bowel diseases and colorectal cancer: a meta-analysis.PMID 21248737Read ↗

Tumor necrosis factor-a polymorphisms and colorectal cancer risk: a meta-analysis.Semantic proximity Read ↗

TNF-α-308 G>A polymorphism and colorectal cancer risk: a meta-analysis.Semantic proximity Read ↗

TNF-α-308 polymorphism and risk of digestive system cancers: a meta-analysis.Semantic proximity Read ↗

TNF-α -308 A allele is associated with an increased risk of distant metastasis in rectal cancer patients from Southwestern China.Semantic proximity Read ↗

Association between TNF-α rs1799724 and rs1800629 polymorphisms and the risk of Crohn's disease.Semantic proximity Read ↗

[Association between tumor necrosis factor alpha gene polymorphism and colorectal cancer].Semantic proximity Read ↗

Association between polymorphism of the tumor necrosis factor alpha-308 gene promoter and colon cancer in the Chinese population.Semantic proximity Read ↗

Polymorphisms of tumor necrosis factor alpha in Middle Eastern population with colorectal cancer.Semantic proximity Read ↗

Association between tumor necrosis factor-α rs1800629 polymorphism and risk of gastric cancer: a meta-analysis.Semantic proximity Read ↗

Tumour necrosis factor-alpha (-308G/A) promoter polymorphism is associated with ulcerative colitis in Brazilian patients.Semantic proximity Read ↗

Associations between single-nucleotide polymorphisms and inflammatory bowel disease-associated colorectal cancers in inflammatory bowel disease patients: a meta-analysis.Semantic proximity Read ↗

The Role of Tumor Necrosis Factor-α (TNF-α) Polymorphisms in Gastric Cancer: a Meta-Analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.