Association between polymorphism of the tumor necrosis factor alpha-308 gene promoter and colon cancer in the Chinese population.

doi:10.1089/gtmb.2011.0068

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Article

Association between polymorphism of the tumor necrosis factor alpha-308 gene promoter and colon cancer in the Chinese population.

Genetic testing and molecular biomarkers - 1 Nov 2011

Li Mingqi, You Qi, Wang Xishan

Abstract excerpt

Tumor necrosis factor (TNF) is a type of cytokine that inhibits tumorigenesis. Several studies have assessed the relationship between the polymorphism of TNF-alpha 308G/A and the susceptibility to colon cancer; however, the results have been controversial. A case-control study was carried out to investigate whether TNF-alpha 308G/A gene polymorphism was associated with the risk of colon cancer in a group of 180...

Topics

Aged
Asian People
China
Colonic Neoplasms
Female
Genetic Predisposition to Disease
Humans
Male
Middle Aged
Polymorphism, Genetic
Promoter Regions, Genetic
Risk Factors
Tumor Necrosis Factor-alpha

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PMID: 21631297
DOI: 10.1089/gtmb.2011.0068

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