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Article

A new mechanism for aging: chemical "age spots" in immortal DNA strands in distributed stem cells.

Breast disease - 1 Jan 2008

Sherley James L

Abstract excerpt

The existence of immortal DNA strands (IDSs) in distributed stem cells (DSCs) of adult human tissues was first inferred by Cairns. Cairns deduced the existence of IDSs by connecting two seemingly disparate observations - one his own and the other belonging to Lark. Cairns noted a mathematical discrepancy between predicted human tissue cell mutation rates and human cancer incidence. He integrated this insight with...

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Identifiers

PMID: 19029623
DOI: 10.3233/bd-2008-29105

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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