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Article

Genetic background modulates gene expression profile induced by skin irradiation in ptch1 mice.

International journal of radiation oncology, biology, physics - 1 Dec 2008

Galvan Antonella, Noci Sara, Mancuso Mariateresa, Pazzaglia Simonetta, Saran Anna, Dragani Tommaso A

Abstract excerpt

PURPOSE: Ptch1 germ-line mutations in mice predispose to radiation-induced basal cell carcinoma of the skin, with tumor incidence modulated by the genetic background. Here, we examined the possible mechanisms underlying skin response to radiation in F1 progeny of Ptch1(neo67/+) mice crossed with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19028281
DOI: 10.1016/j.ijrobp.2008.08.008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19028281-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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