Article
Assessment of genotoxicity of Lidocaine, Prilonest and Septanest in the Drosophila wing-spot test.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association - 1 Jan 2009
Schneider L E, do Amaral V S, Dihl R R, Lehmann M, Reguly M L, de Andrade H H R
Abstract excerpt
The scope of this study was to characterize the likely interaction Lidocaine, Prilonest and Septanest have with DNA, with a view to quantitatively and qualitatively establishing mutagenic, clastogenic, and/or recombinagenic activity of those compounds. The wing somatic mutation and recombination test in Drosophila melanogaster, which detects simultaneously point and chromosomal mutations as well as recombination...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.