Article
Analysis of genotoxic activity of ketamine and rocuronium bromide using the somatic mutation and recombination test in Drosophila melanogaster.
Environmental toxicology and pharmacology - 1 Mar 2015
Koksal Pakize Muge, Gürbüzel Mehmet
Abstract excerpt
The present study evaluated the mutagenic and recombinogenic effects of two commonly used anesthetic agents, ketamine and rocuronium bromide, in medicine using the wing somatic mutation and recombination test (SMART) in Drosophila. The standard (ST) cross and the high-bioactivation (HB) cross with high sensitivity to procarcinogens and promutagens were used. The SMART test is based on the loss of heterozygosity,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
