Article

Six3 and Six6 jointly regulate the identities and developmental trajectories of multipotent retinal progenitor cells in the mouse retina

2023-05-03

Abstract excerpt

Formation, maintenance, and differentiation of tissue-specific progenitor cells are fundamental tasks during organogenesis. Retinal development is an excellent model for dissecting these processes; mechanisms of retinal differentiation can be harnessed for retinal regeneration toward curing blindness. Using single-cell RNA sequencing of embryonic mouse eye cups in which transcription factor Six3 was conditionally...

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Literature Corpus work: 216d7c98-6103-5231-a6d9-acad38e66c4c
DOI: 10.1101/2023.05.03.539288

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