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Article

Missense single nucleotide polymorphism of the ADAM12 gene is associated with radiographic knee osteoarthritis in middle-aged Estonian cohort.

Osteoarthritis and cartilage - 1 Aug 2009

Kerna I, Kisand K, Tamm A E, Lintrop M, Veske K, Tamm A O

Abstract excerpt

OBJECTIVE: One of the recognized candidate genes of osteoarthritis (OA) is the ADAM metallopeptidase domain 12 (meltrin alpha) gene. We investigated the potential role of two single nucleotide polymorphisms (SNP) of the ADAM12 gene in susceptibility to radiographic knee OA and its progression in an Estonian cohort. METHODS: The rs3740199 and rs1871054 polymorphisms were genotyped according to restriction fragment...

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Source

Identifiers

PMID: 19268722
DOI: 10.1016/j.joca.2009.02.006

Genes

ADAM12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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