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Article

Variations in the TNFα gene and their interactions with the IL4R and IL10 genes in relation to hand osteoarthritis.

BMC musculoskeletal disorders - 24 Sept 2014

Hämäläinen Satu, Solovieva Svetlana, Vehmas Tapio, Leino-Arjas Päivi, Hirvonen Ari

Abstract excerpt

BACKGROUND: The development of osteoarthritis (OA) involves inflammation, but the evidence for participation of genes propagating or inhibiting inflammation in the OA process is inconsistent. We investigated the associations of common variants in the TNFα gene, and their interactions with other c...

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Identifiers

PMID: 25252624
DOI: 10.1186/1471-2474-15-311
PMCID: PMC4181701

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25252624-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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