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Article

Somatic hypermutation in autoimmune thyroid disease.

Immunological reviews - 1 Apr 1998

McIntosh R, Watson P, Weetman A

Abstract excerpt

Autoimmune thyroid disease is one of the most common autoimmune diseases. There is typically patient antibody (Ab) reactivity to one or more of the antigens thyroglobulin (Tg), thyroid peroxidase (TPO) and the thyroid simulating hormone receptor (TSHr). With the advent of combinatorial library technology, there has been an enormous increase in the number of sequences from Ab to Tg and TPO. The repertoire of both...

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Source

Identifiers

PMID: 9602367
DOI: 10.1111/j.1600-065x.1998.tb01444.x

Genes

TPO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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