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Article

CpG Island Methylation of Tumor-Related Promoters Occurs Preferentially in Undifferentiated Carcinoma

1 Jul 2006

Abstract excerpt

OBJECTIVE: To understand the role of epigenetic inactivation of tumor-related genes in the pathogenesis of thyroid cancer, we investigated the methylation profile of distinct thyroid neoplasms. DESIGN: We analyzed the methylation pattern of 17 gene promoters in nine thyroid cancer cell lines and in 38 primary thyroid carcinomas (13 papillary thyroid carcinoma [PTC], 10 follicular thyroid carcinoma [FTC], 9...

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Share to Epigenetics and DNA Methylation
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Identifiers

PMID: 16889486
DOI: 10.1089/thy.2006.16.633

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