Article
Immunomodulatory roles of surfactant proteins A and D: implications in lung disease.
Proceedings of the American Thoracic Society - 1 Jul 2007
Pastva Amy M, Wright Jo Rae, Williams Kristi L
Abstract excerpt
Surfactant, a lipoprotein complex, was originally described for its essential role in reducing surface tension at the air-liquid interface of the lung; however, it is now recognized as being a critical component in lung immune host defense. Surfactant proteins (SP)-A and -D are pattern recognition molecules of the collectin family of C-type lectins. SP-A and SP-D are part of the innate immune system and regulate...
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