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Article

Activity of pulmonary surfactant protein-D (SP-D) in vivo is dependent on oligomeric structure.

The Journal of biological chemistry - 1 Jun 2001

Zhang L, Ikegami M, Crouch E C, Korfhagen T R, Whitsett J A

Abstract excerpt

Pulmonary surfactant protein-D (SP-D) is a member of the collectin family of C-type lectins that is synthesized in many tissues including respiratory epithelial cells in the lung. SP-D is assembled predominantly as dodecamers consisting of four homotrimeric subunits each. Association of these subunits is stabilized by interchain disulfide bonds involving two conserved amino-terminal cysteine residues (Cys-15 and...

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Source

Identifiers

PMID: 11278637
DOI: 10.1074/jbc.M010191200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Activity of pulmonary surfactant protein-D (SP-D) in vivo is dependent on oligomeric structure.PMID 11278637Read ↗

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