Article
FGFR-3 and FGFR-4 function cooperatively to direct alveogenesis in the murine lung.
Development (Cambridge, England) - 1 Sept 1998
Weinstein M, Xu X, Ohyama K, Deng C X
Abstract excerpt
Mammalian lungs begin as an outpocket of the foregut, and depend on multiple stages of branching morphogenesis and alveogenesis to reach their final form. An examination of fgf receptor gene expression indicated that all four receptors (fgfr-1 to fgfr-4) are expressed in postnatal lungs at varyin...
Topics
- Animals
- Elastin
- Gene Expression Regulation, Developmental
- Genotype
- Lung
- Mice
- Mutation
- Phenotype
- Polymerase Chain Reaction
- Protein-Tyrosine Kinases
- Pulmonary Alveoli
- Receptor, Fibroblast Growth Factor, Type 3