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The cystic fibrosis transmembrane conductance regulator in reproductive health and disease

17 Nov 2008

Abstract excerpt

The cystic fibrosis transmembrane conductance regulator (CFTR) is an anion channel regulated by cAMP-dependent phosphorylation, which is expressed in epithelial cells of a wide variety of tissues including the reproductive tracts. Mutations in the gene encoding CFTR cause cystic fibrosis, a common genetic disease in Caucasian populations with a multitude of clinical manifestations including...

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PMID: 19015188
DOI: 10.1113/jphysiol.2008.164970

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