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Article

Regulation of male fertility by CFTR and implications in male infertility.

Human reproduction update - 1 Jan 2000

Chen Hui, Ruan Ye Chun, Xu Wen Ming, Chen Jing, Chan Hsiao Chang

Abstract excerpt

BACKGROUND: The cystic fibrosis transmembrane conductance regulator (CFTR) is a cAMP-activated Cl(-) and HCO(3)(-) conducting channel, mutations of which are known to be associated with male infertility. However, the underlying mechanisms remain elusive. METHODS: Literature databases were searched for papers on the topics related to CFTR and male fertility and infertility with relevant keywords. Unpublished data...

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Source

Identifiers

PMID: 22709980
DOI: 10.1093/humupd/dms027

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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