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The Physiology of Bicarbonate Transporters in Mammalian Reproduction1

20 Jan 2012

Abstract excerpt

HCO(3)(-) plays critically important roles during virtually the entire process of reproduction in mammals, including spermatogenesis, sperm capacitation, fertilization, and development of early stage embryos. Therefore, the acid-base balance in the male and female reproductive tracts must be finely modulated. The fluid milieu in the epididymis is acidic, containing very low concentration of HCO(3)(-). In this...

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PMID: 22262691
DOI: 10.1095/biolreprod.111.096826

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