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Article

The biogenesis, traffic, and function of the cystic fibrosis transmembrane conductance regulator.

International review of cytology - 1 Jan 1997

Jilling T, Kirk K L

Abstract excerpt

The cystic fibrosis transmembrane conductance regulator (CFTR) is a cyclic AMP-activated chloride channel that is encoded by the gene that is defective in cystic fibrosis. This ion channel resides at the luminal surfaces and in endosomes of epithelial cells that line the airways, intestine, and a variety of exocrine glands. In this article we discuss current hypotheses regarding how CFTR functions as a regulated...

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Source

Identifiers

PMID: 9102394
DOI: 10.1016/s0074-7696(08)62361-x

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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