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The interactome of cystic fibrosis transmembrane conductance regulator and its role in male fertility: A critical review

26 Sept 2024

Abstract excerpt

The cystic fibrosis transmembrane conductance regulator (CFTR) is a cyclic adenosine monophosphate (cAMP)-regulated chloride and bicarbonate ion channel found in many human cells. Its unique biochemical characteristics and role as a member of the adenosine triphosphate (ATP)-binding cassette transporters superfamily are pivotal for the transport of several substrates across cellular membranes. CFTR is known to...

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PMID: 39324358
DOI: 10.1002/jcp.31422

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