Beyond obstructive azoospermia: emerging insights into reproductive health in men with cystic fibrosis.

Abstract excerpt

Cystic fibrosis (CF) is a genetic disorder caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene and is classically associated with male infertility due to obstructive azoospermia secondary to congenital bilateral absence of the vas deferens. Increasing evidence suggests that CFTR dysfunction may also contribute to nonobstructive forms of male infertility. Accordingly, CFTR is...

Topics

• Humans
• Male
• Azoospermia
• Cystic Fibrosis Transmembrane Conductance Regulator
• Cystic Fibrosis
• Spermatogenesis