Article
CFTR!
The American journal of physiology - 1 Aug 1992
Fuller C M, Benos D J
Abstract excerpt
Cystic fibrosis (CF) is a fatal genetic disease primarily affecting Caucasians, although cases have been reported from other ethnic groups. CF has a complex etiology, but it is chiefly a disease of electrolyte transport and is characterized by defects in fluid secretion by several epithelia, including the sweat duct, exocrine pancreas, and the pulmonary airways. The link between CF and a defect in cAMP-mediated...
Topics
- Adenosine Triphosphate
- Biological Transport
- Chloride Channels
- Cystic Fibrosis
- Cystic Fibrosis Transmembrane Conductance Regulator
- Humans
- Ions
- Membrane Proteins
- Mutation
- Peptide Mapping