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Article

Glycosylphosphatidylinositol-anchored protein deficiency confers resistance to apoptosis in PNH.

Experimental hematology - 1 Jan 2009

Savage William J, Barber James P, Mukhina Galina L, Hu Rong, Chen Guibin, Matsui William, Thoburn Chris, Hess Allan D, Cheng Linzhao, Jones Richard J, Brodsky Robert A

Abstract excerpt

OBJECTIVE: Investigate the contribution of PIG-A mutations to clonal expansion in paroxysmal nocturnal hemoglobinuria (PNH). MATERIALS AND METHODS: Primary CD34+ hematopoietic progenitors from PNH patients were assayed for annexin-V positivity by flow cytometry in a cell-mediated killing assay us...

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Source

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Identifiers

PMID: 19013003
DOI: 10.1016/j.exphem.2008.09.002
PMCID: PMC2628761

Genes

GPI
TNF
ULBP1
ULBP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19013003-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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