Article
Plasma from patients with sepsis up-regulates the expression of CD49d and CD64 on blood neutrophils.
American journal of respiratory cell and molecular biology - 1 Jun 2009
Lewis Sion M, Treacher David F, Bergmeier Lesley, Brain Susan D, Chambers David J, Pearson Jeremy D, Brown Kenneth A
Abstract excerpt
An excessive interaction of blood neutrophils with microvascular walls may underlie the organ failure of sepsis. In this study, flow cytometric analysis was used to investigate whether plasma from 22 patients with sepsis altered the expression of the adhesion molecules (CD11a, CD11b, CD49d, and CD62L) on normal blood neutrophils and enhanced their binding to cultured endothelium. Most of the plasma samples from...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
