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Article

Modulation of the endotoxin receptor (CD14) in septic patients.

The Journal of trauma - 1 Apr 1992

Birkenmaier C, Hong Y S, Horn J K

Abstract excerpt

The monocyte is a pivotal cell in septic patients that responds to endotoxin with release of inflammatory cytokines. Monocytes display on their surface a receptor (CD14) for complexes formed by endotoxin (lipopolysaccharide, LPS) and a plasma LPS-binding protein (LBP). We compared monocytes obtained from normal controls with those obtained from septic patients for expression of CD14 by flow cytometric analysis of...

Topics

Antigens, CD
Antigens, Differentiation, Myelomonocytic
Bacteremia
CD11 Antigens
Cells, Cultured
Escherichia coli
Flow Cytometry
Gene Expression Regulation, Bacterial
Humans
Injury Severity Score
Lipopolysaccharide Receptors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lipopolysaccharides

Monocytes

Multiple Organ Failure

Phenotype

Receptors, Immunologic

Source

Identifiers

PMID: 1373777

Genes

LBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1373777-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Modulation of the endotoxin receptor (CD14) in septic patients.PMID 1373777Read ↗

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