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Article

Single nucleotide polymorphisms in chromosomal instability genes and risk and clinical outcome of breast cancer: a Swedish prospective case-control study.

European journal of cancer (Oxford, England : 1990) - 1 Feb 2009

Brendle Annika, Brandt Andreas, Johansson Robert, Enquist Kerstin, Hallmans Göran, Hemminki Kari, Lenner Per, Försti Asta

Abstract excerpt

Chromosomal instability (CIN) is a major characteristic of many cancers. We investigated whether putatively functional single nucleotide polymorphisms (SNPs) in genes related to CIN (CENPF, ESPL1, NEK2, PTTG1, ZWILCH, ZWINT) affect breast cancer (BC) risk and clinical outcome in a Swedish cohort of 749 incident BC cases with detailed clinical data and up to 15 years of follow-up and 1493 matched controls. As a...

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Source

Identifiers

PMID: 19008095
DOI: 10.1016/j.ejca.2008.10.001

Genes

CENPF
ESPL1
NEK2
PTTG1
ZWILCH
ZWINT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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