Article
Prognostic impact of polymorphisms in the MYBL2 interacting genes in breast cancer.
Breast cancer research and treatment - 1 Feb 2012
Shi Hong, Bevier Melanie, Johansson Robert, Enquist-Olsson Kerstin, Henriksson Roger, Hemminki Kari, Lenner Per, Försti Asta
Abstract excerpt
MYBL2 is a transcription factor, which regulates the expression of genes involved in cancer progression. In this study, we investigated whether putative functional variants in genes regulating MYBL2 (E2F1, E2F3 and E2F4) or in genes, which are regulated by MYBL2 (BCL2, BIRC5, COL1A1, COL1A2, COL5A2, ERBB2, CLU, LIN9 and TOP2A) affect breast cancer (BC) susceptibility and clinical outcome. Twenty-eight SNPs were...
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