Article
Genetic Variants Detected Using Cell-Free DNA from Blood and Tumor Samples in Patients with Inflammatory Breast Cancer.
International journal of molecular sciences - 14 Feb 2020
Winn Jennifer S, Hasse Zachary, Slifker Michael, Pei Jianming, Arisi-Fernandez Sebastian M, Talarchek Jacqueline N, Obeid Elias, Baldwin Donald A, Gong Yulan, Ross Eric, Cristofanilli Massimo, Alpaugh R Katherine, Fernandez Sandra V
Abstract excerpt
We studied genomic alterations in 19 inflammatory breast cancer (IBC) patients with advanced disease using samples of tissue and paired blood serum or plasma (cell-free DNA, cfDNA) by targeted next generation sequencing (NGS). At diagnosis, the disease was triple negative (TN) in eleven patients (57.8%), ER+ Her2- IBC in six patients (31.6%), ER+ Her2+ IBC in one patient (5.3%), and ER- Her2+ IBC in one other...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
