Article
Frequent polymorphic variations but rare tumour specific mutations of the S100A2 on 1q21 in non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands) - 1 Mar 2009
Strazisar Mojca, Rott Tomaz, Glavac Damjan
Abstract excerpt
Contrary to the recent hypothesis that S100A2 is a tumour suppressor, no somatic mutations have yet been identified. We therefore screened 90 non-small cell lung carcinoma (NSCLC) samples, initially for mutations in S100A2 and then also for mutations in P53 and K-RAS genes. Alterations were detec...
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