Article
AURKA overexpression accompanies dysregulation of DNA-damage response genes in invasive urothelial cell carcinoma.
Cell cycle (Georgetown, Tex.) - 15 Nov 2008
Veerakumarasivam Abhi, Goldstein Leonard D, Saeb-Parsy Kasra, Scott Helen E, Warren Anne, Thorne Natalie P, Mills Ian G, Venkitaraman Ashok, Neal David E, Kelly John D
Abstract excerpt
Invasive urothelial cell carcinoma (UCC) is characterized by increased chromosomal instability and follows an aggressive clinical course in contrast to non-invasive disease. To identify molecular processes that confer and maintain an aggressive malignant phenotype, we used a high-throughput genom...
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