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Article

Integrated genomic and gene expression profiling identifies two major genomic circuits in urothelial carcinoma.

PloS one - 1 Jan 2012

Lindgren David, Sjödahl Gottfrid, Lauss Martin, Staaf Johan, Chebil Gunilla, Lövgren Kristina, Gudjonsson Sigurdur, Liedberg Fredrik, Patschan Oliver, Månsson Wiking, Fernö Mårten, Höglund Mattias

Abstract excerpt

Similar to other malignancies, urothelial carcinoma (UC) is characterized by specific recurrent chromosomal aberrations and gene mutations. However, the interconnection between specific genomic alterations, and how patterns of chromosomal alterations adhere to different molecular subgroups of UC, is less clear. We applied tiling resolution array CGH to 146 cases of UC and identified a number of regions harboring...

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Share to Carcinoma, Transitional Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins c-mdm2

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Source

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Identifiers

PMID: 22685613
DOI: 10.1371/journal.pone.0038863
PMCID: PMC3369837

Genes

CCND1
CCNE1
FGFR3
MDM2
PTEN
SETDB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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