Article
Polygenic model for predicting breast cancer risk via genome-wide polymorphisms.
AMIA ... Annual Symposium proceedings. AMIA Symposium - 6 Nov 2008
Piccolo Stephen R, Camp Nicola, Frey Lewis J
Abstract excerpt
A polygenic model for predicting susceptibility to late-onset, sporadic forms of breast-cancer based on an individual's SNP profile was developed. The model was validated using a publicly available data set with genome-wide SNP markers for cases and controls. Preliminary results show that this method performs better than expected by chance.
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