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Article

Polygenic inherited predisposition to breast cancer.

Cold Spring Harbor symposia on quantitative biology - 1 Jan 2005

Ponder B A J, Antoniou A, Dunning A, Easton D F, Pharoah P D P

Abstract excerpt

The known breast cancer predisposing genes account for only about 20% of inherited susceptibility. Epidemiological analyses suggest that much of the remaining 80% is explained by the combined effect of many individually weak genetic variants, rather than by further rare, highly penetrant mutation...

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Identifiers

PMID: 16869736
DOI: 10.1101/sqb.2005.70.029

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16869736-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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