Article
Plasma levels of complement proteins from the alternative pathway in patients with age-related macular degeneration are independent of Complement Factor H Tyr⁴⁰²His polymorphism.
Molecular vision - 1 Jan 2012
Silva Aldacilene Souza, Teixeira Anderson Gustavo, Bavia Lorena, Lin Fabio, Velletri Roberta, Belfort Rubens, Isaac Lourdes
Abstract excerpt
PURPOSE: To investigate the influence of the Factor H (CFH) Tyr⁴⁰²His polymorphism on the plasma levels of the alternative pathway proteins CFH, C3, Factor B (FB), Factor D (FD), and Factor I (FI) and the inflammatory marker C-reactive protein (CRP) in 119 patients with age-related macular degeneration (AMD) and 152 unrelated control individuals. METHODS: Patients with AMD and the control group were separated...
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