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Article

Glucocorticoid-induced leucine zipper is protective in Th1-mediated models of colitis.

Gastroenterology - 1 Feb 2009

Cannarile Lorenza, Cuzzocrea Salvatore, Santucci Luca, Agostini Massimiliano, Mazzon Emanuela, Esposito Emanuela, Muià Carmelo, Coppo Maddalena, Di Paola Rosanna, Riccardi Carlo

Abstract excerpt

BACKGROUND & AIMS: Inflammatory bowel diseases are relatively common diseases of the gastrointestinal tract. The relative therapeutic efficacy of glucocorticoids used in inflammatory bowel diseases resides in part in their capability to inhibit activity of nuclear factor kappaB (NF-kappaB), a transcription factor central to the inflammatory process, and the consequent production of T-helper 1 (Th1)-type...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18996377
DOI: 10.1053/j.gastro.2008.09.024

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Glucocorticoid-induced leucine zipper is protective in Th1-mediated models of colitis.PMID 18996377Read ↗

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