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Article

Oligomerisation of Tube and Pelle leads to nuclear localisation of dorsal.

Mechanisms of development - 1 Mar 1999

Grosshans J, Schnorrer F, Nüsslein-Volhard C

Abstract excerpt

In the Drosophila embryo the nuclear localisation of Dorsal, a member of the Rel family, is regulated by an extracellular signal, which is transmitted to the interior of the egg cell by a cascade of proteins involving the novel protein Tube and the protein kinase Pelle. Here we analyse the activation mechanism of Tube and Pelle and the interaction between these two components. We show that both proteins, although...

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Identifiers

PMID: 10330490
DOI: 10.1016/s0925-4773(98)00236-6

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Oligomerisation of Tube and Pelle leads to nuclear localisation of dorsal.PMID 10330490Read ↗

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