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Article

Low-penetrance alleles predisposing to sporadic colorectal cancers: a French case-controlled genetic association study.

BMC cancer - 7 Nov 2008

Küry Sébastien, Buecher Bruno, Robiou-du-Pont Sébastien, Scoul Catherine, Colman Hélène, Le Neel Tanguy, Le Houérou Claire, Faroux Roger, Ollivry Jean, Lafraise Bernard, Chupin Louis-Dominique, Sébille Véronique, Bézieau Stéphane

Abstract excerpt

BACKGROUND: Sporadic colorectal cancers (CRC) are multifactorial diseases resulting from the combined effects of numerous genetic, environmental and behavioral risk factors. Genetic association studies have suggested low-penetrance alleles of extremely varied genes to be involved in susceptibilit...

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Source

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Identifiers

PMID: 18992148
DOI: 10.1186/1471-2407-8-326
PMCID: PMC2585099

Genes

MTHFR
PPARG
PTGS1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18992148-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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