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Article

Generation of c-Fos knockout rats, and observation of their phenotype.

Experimental animals - 21 Feb 2023

Yoshimura Yuki, Nakamura Kazuomi, Seno Misako, Mochizuki Misa, Kawai Kenji, Koba Satoshi, Watanabe Tatsuo

Abstract excerpt

c-Fos is a useful marker gene of neuron activation for neuroscience and physiology research. The mechanism and function of neural networks have been elucidated using c-Fos reporter knock-in (KI) mice, but the small size of the mice makes it difficult to perform surgical procedures on specific brain regions. On the other hand, there is a large amount of accumulated data on behavioral studies using rats. Thus, the...

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Identifiers

PMID: 36216550
DOI: 10.1538/expanim.22-0077
PMCID: PMC9978135

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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