Influence of the cytocidal macrophage phenotype on the degradation of acetylated low density lipoproteins: dual regulation of scavenger receptor activity and of intracellular degradation of endocytosed ligand.

doi:10.1016/0014-4827(91)90065-3

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Article

Influence of the cytocidal macrophage phenotype on the degradation of acetylated low density lipoproteins: dual regulation of scavenger receptor activity and of intracellular degradation of endocytosed ligand.

Experimental cell research - 1 Feb 1991

De Whalley C V, Riches D W

Abstract excerpt

The appearance of lipid-laden macrophages is a characteristic feature in the development of the atherosclerotic plaque. The functional status of macrophages located within the intima of atherosclerotic lesions is as yet unknown; nevertheless, macrophages are known to be exceedingly responsive to their environment and can differentiate to different functional states. The objective of this study was to determine...

Topics

Animals
Endocytosis
In Vitro Techniques
Interferon-gamma
Kinetics
Lipopolysaccharides
Lipoproteins, LDL
Macrophages
Membrane Proteins
Mice
Mice, Inbred C3H

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Poly I-C

Receptors, Immunologic

Receptors, Lipoprotein

Receptors, Scavenger

Scavenger Receptors, Class B

Source

Open in PubMed

Identifiers

PMID: 1899073
DOI: 10.1016/0014-4827(91)90065-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1899073-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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