Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interaction of Macrophages and Cholesterol-Dependent Cytolysins: The Impact on Immune Response and Cellular Survival

19 Aug 2020

Abstract excerpt

Cholesterol-dependent cytolysins (CDCs) are key virulence factors involved in many lethal bacterial infections, including pneumonia, necrotizing soft tissue infections, bacterial meningitis, and miscarriage. Host responses to these diseases involve myeloid cells, especially macrophages. Macrophages use several systems to detect and respond to cholesterol-dependent cytolysins, including membrane repair,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Infections and Vaccines
Share to Inflammasome and immune disorders
Share to Streptococcal Infections and Treatments

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32825096
DOI: 10.3390/toxins12090531

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interaction of Macrophages and Cholesterol-Dependent Cytolysins: The Impact on Immune Response and Cellular SurvivalPMID 32825096Read ↗

Reprogramming cholesterol metabolism in macrophages and its role in host defense against cholesterol-dependent cytolysinsSemantic proximity Read ↗

Autophagy in Macrophages: Impacting Inflammation and Bacterial InfectionSemantic proximity Read ↗

Macrophages in Microbial Pathogenesis: Commonalities of Defense Evasion MechanismsSemantic proximity Read ↗

Pneumolysin: Pathogenesis and Therapeutic TargetSemantic proximity Read ↗

The role of lipids in host–pathogen interactionsSemantic proximity Read ↗

Impact of cholesterol on disease progressionSemantic proximity Read ↗

Group A Streptococcus Encounters with Host MacrophagesSemantic proximity Read ↗

Autophagy, cell death, and cytokines in K. pneumoniae infection: therapeutic perspectivesSemantic proximity Read ↗

Macrophages and autophagy: partners in crimeSemantic proximity Read ↗

Monocytes and Macrophages in COVID-19Semantic proximity Read ↗

Macrophage LC3-associated phagocytosis is an immune defense against Streptococcus pneumoniae that diminishes with host agingSemantic proximity Read ↗

Group A Streptococcus induces lysosomal dysfunction in THP-1 macrophagesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.