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Article

Implications of lipid raft disintegration: enhanced anti-inflammatory macrophage phenotype.

Surgery - 1 Aug 2004

Cuschieri Joseph

Abstract excerpt

BACKGROUND: Lipid rafts are membrane microdomains characterized by an enriched cholesterol environment and appear to serve as a platform for signaling. Their role within the macrophage during endotoxin exposure is unknown. METHODS: THP-1 cells were subjected to lipopolysaccharide stimulation with or without methyl-beta-cyclodextrin (MbetaCD) pretreatment, a cholesterol depleting agent. Cell surface expression of...

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Source

Identifiers

PMID: 15300176
DOI: 10.1016/j.surg.2004.04.009

Genes

TLR4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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