Article
Estrogen receptor alpha polymorphism and susceptibility to uterine leiomyoma.
Steroids - 1 Nov 2006
Villanova Fabiola E, Andrade Priscila M, Otsuka Audrey Y, Gomes Mariano T V, Leal Elcio S, Castro Rodrigo A, Girão Manoel J B C, Nishimura Eddy, Baracat Edmund C, Silva Ismael D C G
Abstract excerpt
Uterine leiomyoma is the most frequent pelvic tumor found in female genital tract. Some studies have suggested an association between single nucleotide polymorphisms (SNPs) in estrogen receptors genes with susceptibility in developing uterine leiomyoma. In this work, we estimated the frequency of two SNPs: one located in the intron 1 (rs9322331) and other in the exon 1 (rs17847075) of the estrogen receptor alpha...
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