Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional Characterisation of the Autophagy ATG12~5/16 Complex in Dictyostelium discoideum.

Cells - 9 May 2020

Karow Malte, Fischer Sarah, Meßling Susanne, Konertz Roman, Riehl Jana, Xiong Qiuhong, Rijal Ramesh, Wagle Prerana, Clemen Christoph S, Eichinger Ludwig

Abstract excerpt

Macroautophagy, a highly conserved and complex intracellular degradative pathway, involves more than 20 core autophagy (ATG) proteins, among them the hexameric ATG12~5/16 complex, which is part of the essential ubiquitin-like conjugation systems in autophagy. Dictyostelium discoideumatg5 single, atg5/12 double, and atg5/12/16 triple gene knock-out mutant strains displayed similar defects in the conjugation of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy
Share to Autophagy-Related Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Conserved Sequence

Share to Dictyostelium

Share to Phagocytosis

Share to Pinocytosis

Share to Proteostasis

Share to Protozoan Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 32397394
DOI: 10.3390/cells9051179
PMCID: PMC7290328

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional Characterisation of the Autophagy ATG12~5/16 Complex in Dictyostelium discoideum.PMID 32397394Read ↗

The phenotypes of ATG9, ATG16 and ATG9/16 knock-out mutants imply autophagy-dependent and -independent functions.Semantic proximity Read ↗

The two Dictyostelium discoideum autophagy 8 proteins have distinct autophagic functions.Semantic proximity Read ↗

Loss of Dictyostelium ATG9 results in a pleiotropic phenotype affecting growth, development, phagocytosis and clearance and replication of Legionella pneumophilaSemantic proximity Read ↗

Dictyostelium macroautophagy mutants vary in the severity of their developmental defects.Semantic proximity Read ↗

Macroautophagy is dispensable for intracellular replication of Legionella pneumophila in Dictyostelium discoideumSemantic proximity Read ↗

Autophagy inDictyostelium: Mechanisms, regulation and disease in a simple biomedical modelSemantic proximity Read ↗

Macroautophagy is required for multicellular development of the social amoeba Dictyostelium discoideum.Semantic proximity Read ↗

The Multifaceted Interactions of Dictyostelium Atg1 with Mitochondrial Function, Endocytosis, Growth, and Development.Semantic proximity Read ↗

Autophagy in Dictyostelium: Genes and pathways, cell death and infectionSemantic proximity Read ↗

Dissecting the function of Atg1 complex in Dictyostelium autophagy reveals a connection with the pentose phosphate pathway enzyme transketolase.Semantic proximity Read ↗

Mycobacterium marinum antagonistically induces an autophagic response while repressing the autophagic flux in a TORC1- and ESX-1-dependent mannerSemantic proximity Read ↗

Calnexin, calreticulin and cytoskeleton-associated proteins modulate uptake and growth of Legionella pneumophila in Dictyostelium discoideum.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.