Article
A common haplotype of DRD3 affected by recent positive selection is associated with protection from schizophrenia.
Human genetics - 1 Jan 2009
Costas Javier, Carrera Noa, Domínguez Eduardo, Vilella Elisabet, Martorell Lourdes, Valero Joaquín, Gutiérrez-Zotes Alfonso, Labad Antonio, Carracedo Angel
Abstract excerpt
The number and frequency of susceptibility alleles at loci associated to most psychiatric disorders is largely unknown, in spite of its relevance for the design of studies aiming to find these alleles. Both, common polymorphisms and rare mutations may contribute to the genetic susceptibility to c...
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