Article
Extensive linkage disequilibrium mapping at HTR2A and DRD3 for schizophrenia susceptibility genes in the Galician population.
Schizophrenia research - 1 Feb 2007
Domínguez Eduardo, Loza María Isabel, Padín Fernando, Gesteira Alejandro, Paz Eduardo, Páramo Mario, Brenlla Julio, Pumar Estefanía, Iglesias Fernanda, Cibeira Alcira, Castro Marián, Caruncho Héctor, Carracedo Angel, Costas Javier
Abstract excerpt
The serotonin and dopamine neurotransmitter systems are candidate pathways in the development of schizophrenia because of the assumed causal relationship with the observed symptoms as well as effective targeting of the corresponding receptors by antipsychotic drugs. However, genetic association studies have systematically focused on a limited set of genes and single nucleotide polymorphisms (SNPs), including...
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