Article
Association study of DRD3 gene in schizophrenia in Mexican sib-pairs.
Psychiatry research - 30 Dec 2011
Urraca Nora, Camarena Beatriz, Aguilar Alejandro, Fresán Ana, Apiquián Rogelio, Orozco Lorena, Carnevale Alessandra, Nicolini Humberto
Abstract excerpt
Schizophrenia is a heritable, complex mental disorder. We analysed the DRD3 gene as a candidate to be related to schizophrenia and clinical features in affected sib-pairs. A positive association with the -250A/Ser9 haplotype and a trend toward an association with formal thought disorder were observed. A synergic effect of DRD3 polymorphisms on schizophrenia susceptibility is suggested.
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