Article
The dopamine D3 receptor (DRD3) gene and risk of schizophrenia: case-control studies and an updated meta-analysis.
Schizophrenia research - 1 Jan 2010
Nunokawa Ayako, Watanabe Yuichiro, Kaneko Naoshi, Sugai Takuro, Yazaki Saori, Arinami Tadao, Ujike Hiroshi, Inada Toshiya, Iwata Nakao, Kunugi Hiroshi, Sasaki Tsukasa, Itokawa Masanari, Ozaki Norio, Hashimoto Ryota, Someya Toshiyuki
Abstract excerpt
The dopamine D3 receptor (DRD3) has been suggested to be involved in the pathophysiology of schizophrenia. DRD3 has been tested for an association with schizophrenia, but with conflicting results. A recent meta-analysis suggested that the haplotype T-T-T-G for the SNPs rs7631540-rs1486012-rs2134655-rs963468 may confer protection against schizophrenia. However, almost all previous studies of the association...
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