Article
Genetic variants of the HLA-A, HLA-B and AIF1 loci show independent associations with type 1 diabetes in Norwegian families.
Genes and immunity - 1 Mar 2009
Eike M C, Olsson M, Undlien D E, Dahl-Jørgensen K, Joner G, Rønningen K S, Thorsby E, Lie B A
Abstract excerpt
The main genetic predisposition to type 1 diabetes (T1D) is known to be conferred by the HLA-DRB1, -DQA1 and -DQB1 genes in the major histocompatibility complex (MHC). Other genetic factors within this complex are known to contribute, but their identity has often been controversial. This picture...
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