Article
Detection of genetic association and a functional polymorphism of dynamin 1 gene with nicotine dependence in European and African Americans.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Apr 2009
Xu Qing, Huang Weihua, Payne Thomas J, Ma Jennie Z, Li Ming D
Abstract excerpt
Although it has been documented that dynamin 1 gene (DNM1) is significantly modulated by nicotine in animal models, its association with nicotine dependence (ND) in human population remained to be unexplored. To determine whether DNM1 is associated with ND, in this study, we genotyped seven single-nucleotide polymorphisms (SNPs) within this gene in 602 nuclear families of either African-American (AA) or...
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