Article
Requirement for a core 1 galactosyltransferase in the Drosophila nervous system.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Dec 2008
Lin Yuh-Ru, Reddy B V V G, Irvine Kenneth D
Abstract excerpt
Mucin type O-glycosylation is a widespread modification of eukaryotic proteins, but its functional requirements remain incompletely understood. It is initiated by the attachment of N-acetylgalactosamine (GalNAc) to Ser or Thr residues, and then elongated by additional sugars. We have examined requirements for mucin-type glycosylation in Drosophila by characterizing the expression and phenotypes of core 1...
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